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Details on Person The centrosomal protein C-Nap1 is thought to play an importa...

Class:IdSummation:380720
_displayNameThe centrosomal protein C-Nap1 is thought to play an importa...
_timestamp2008-11-24 15:17:10
created[InstanceEdit:380719] Matthews, L, 2008-11-14 09:59:04
literatureReference[LiteratureReference:380702] The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion
[LiteratureReference:380721] C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2
[LiteratureReference:380718] The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles
modified[InstanceEdit:380723] Matthews, L, 2008-11-14 09:59:23
[InstanceEdit:383220] Matthews, L, 2008-11-24 15:16:28
textThe centrosomal protein C-Nap1 is thought to play an important role in centrosome cohesion during interphase (Fry et al.,1998). At the onset of mitosis, when centrosomes separate to form the bipolar spindle, C-Nap1 dissociates (Mayor et al., 2000). Dissociation of C-Nap1 from mitotic centrosomes appears to be regulated by phosphorylation (Mayor et al. 2002).
(summation)[Reaction:380294] Loss of C-Nap-1 from centrosomes [Homo sapiens]
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