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Details on Person tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate

Class:Id	Reaction:379980
_displayName	tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate
_doRelease	TRUE
_timestamp	2010-04-12 22:27:09
authored	[InstanceEdit:386989] D'Eustachio, P, 2008-11-29 15:41:00
catalystActivity	[CatalystActivity:379577] tyrosine-tRNA ligase activity of YARS dimer [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:379999] D'Eustachio, P, 2008-11-06 23:24:17
edited	[InstanceEdit:386989] D'Eustachio, P, 2008-11-29 15:41:00
input	[SimpleEntity:29506] L-Tyr [cytosol] [GenomeEncodedEntity:379743] tRNA(Tyr) [cytosol] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:379987] Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains [LiteratureReference:389210] Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy
modified	[InstanceEdit:380054] D'Eustachio, P, 2008-11-06 23:26:11 [InstanceEdit:383273] D'Eustachio, P, 2008-11-24 15:45:47 [InstanceEdit:386990] D'Eustachio, P, 2008-11-29 15:46:40 [InstanceEdit:387427] D'Eustachio, P, 2008-12-02 17:01:51 [InstanceEdit:389226] D'Eustachio, P, 2008-12-23 21:44:12 [InstanceEdit:589907] D'Eustachio, P, 2010-04-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate
output	[GenomeEncodedEntity:379785] Tyr-tRNA(Tyr) [cytosol] [Homo sapiens] [SimpleEntity:76577] AMP [cytosol] [SimpleEntity:111294] PPi [cytosol]
releaseDate	2008-12-17
reviewed	[InstanceEdit:387428] Antonellis, A, 2008-12-02 16:58:45
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:389225] D'Eustachio, P, 2008-12-23 21:40:28
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:387753] R-HSA-379980.2
summation	[Summation:380039] YARS (cytosolic tyrosyl tRNA synthetase) catalyzes the react...
(hasEvent)	[Pathway:379716] Cytosolic tRNA aminoacylation [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9782462] Update Tracker - [Reaction:379980] tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate - v59:[modifyText] [_UpdateTracker:9789636] Update Tracker - [Reaction:379980] tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate - v37:[modifyText] [_UpdateTracker:9790586] Update Tracker - [Reaction:379980] tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate - v33:[add_removeInput] [_UpdateTracker:9791641] Update Tracker - [Reaction:379980] tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate - v28:[addLiteratureReference, modifyText]
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No pathways have been reviewed or authored by tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate (379980)