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Details on Person isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate

Class:Id	Reaction:379893
_displayName	isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate
_doRelease	TRUE
_timestamp	2008-12-03 09:57:11
authored	[InstanceEdit:386989] D'Eustachio, P, 2008-11-29 15:41:00
catalystActivity	[CatalystActivity:379599] isoleucine-tRNA ligase activity of aminoacyl-tRNA synthetase multienzyme complex [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:379895] D'Eustachio, P, 2008-11-05 23:22:56
edited	[InstanceEdit:386989] D'Eustachio, P, 2008-11-29 15:41:00
input	[SimpleEntity:30102] L-Ile [cytosol] [GenomeEncodedEntity:379739] tRNA(Ile) [cytosol] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:379897] Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit
modified	[InstanceEdit:379899] D'Eustachio, P, 2008-11-05 23:23:08 [InstanceEdit:383273] D'Eustachio, P, 2008-11-24 15:45:47 [InstanceEdit:386990] D'Eustachio, P, 2008-11-29 15:46:40 [InstanceEdit:387427] D'Eustachio, P, 2008-12-02 17:01:51 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate
output	[GenomeEncodedEntity:379787] Ile-tRNA(Ile) [cytosol] [Homo sapiens] [SimpleEntity:76577] AMP [cytosol] [SimpleEntity:111294] PPi [cytosol]
releaseDate	2008-12-17
reviewed	[InstanceEdit:387428] Antonellis, A, 2008-12-02 16:58:45
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:387777] R-HSA-379893.2
summation	[Summation:379896] IARS (cytosolic aspartyl tRNA synthetase) catalyzes the reac...
(hasEvent)	[Pathway:379716] Cytosolic tRNA aminoacylation [Homo sapiens]
(inferredFrom)	[Reaction:1113150] isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate [Oryza sativa]
(orthologousEvent)	[Reaction:1113150] isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate [Oryza sativa]
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No pathways have been reviewed or authored by isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate (379893)