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Details on Person phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate

Class:Id	Reaction:379848
_displayName	phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate
_doRelease	TRUE
_timestamp	2008-12-03 09:55:47
authored	[InstanceEdit:386989] D'Eustachio, P, 2008-11-29 15:41:00
catalystActivity	[CatalystActivity:379621] phenylalanine-tRNA ligase activity of FARS A2B2 tetramer [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:379847] D'Eustachio, P, 2008-11-05 23:09:57
edited	[InstanceEdit:386989] D'Eustachio, P, 2008-11-29 15:41:00
input	[SimpleEntity:29502] L-Phe [cytosol] [GenomeEncodedEntity:379767] tRNA(Phe) [cytosol] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:379891] Cloning and expression of human phenylalanyl-tRNA synthetase in Escherichia coli: comparative study of purified recombinant enzymes
modified	[InstanceEdit:379892] D'Eustachio, P, 2008-11-05 23:10:56 [InstanceEdit:383273] D'Eustachio, P, 2008-11-24 15:45:47 [InstanceEdit:386990] D'Eustachio, P, 2008-11-29 15:46:40 [InstanceEdit:387427] D'Eustachio, P, 2008-12-02 17:01:51 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate
output	[GenomeEncodedEntity:379792] Phe-tRNA(Phe) [cytosol] [Homo sapiens] [SimpleEntity:76577] AMP [cytosol] [SimpleEntity:111294] PPi [cytosol]
releaseDate	2008-12-17
reviewed	[InstanceEdit:387428] Antonellis, A, 2008-12-02 16:58:45
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:387591] R-HSA-379848.2
summation	[Summation:379886] FARS (cytosolic phenylalanyl tRNA synthetase) catalyzes the ...
(hasEvent)	[Pathway:379716] Cytosolic tRNA aminoacylation [Homo sapiens]
(inferredFrom)	[Reaction:1113144] phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate [Oryza sativa]
(orthologousEvent)	[Reaction:1113144] phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate [Oryza sativa]
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No pathways have been reviewed or authored by phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate (379848)