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Details on Person Mitochondrial tRNA synthetases act in the mitochondrial matr...
| Class:Id | Summation:379733 |
|---|---|
| _displayName | Mitochondrial tRNA synthetases act in the mitochondrial matr... |
| _timestamp | 2011-07-14 17:07:55 |
| created | [InstanceEdit:379702] D'Eustachio, P, 2008-11-04 23:29:06 |
| modified | [InstanceEdit:380818] D'Eustachio, P, 2008-11-14 18:28:23 [InstanceEdit:1449551] D'Eustachio, P, 2011-07-14 |
| text | Mitochondrial tRNA synthetases act in the mitochondrial matrix to catalyze the reactions of tRNAs encoded in the mitochondrial genome, their cognate amino acids, and ATP to form aminoacyl-tRNAs, AMP, and pyrophosphate (Schneider et al. 2000). The synthetase enzymes that catalyze these reactions are all encoded in the nuclear genome. In three cases, glycine, lysine, and glutamine, a single gene encodes two enzyme isoforms, one cytosolic and one mitochondrial. All other mitochondrial tRNA synthetases are encoded by genes different from the ones encoding the corresponding cytosolic enzymes. |
| (summation) | [Pathway:379726] Mitochondrial tRNA aminoacylation [Homo sapiens] |
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No pathways have been reviewed or authored by Mitochondrial tRNA synthetases act in the mitochondrial matr... (379733)
