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Details on Person SHC binds to phosphorylated EGFR

Class:Id	Reaction:379166
_displayName	SHC binds to phosphorylated EGFR
_doRelease	FALSE
_timestamp	2017-06-27 17:38:17
authored	[InstanceEdit:386949] Williams, MG, 2008-10-09 16:49:12
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:379213] Williams, MG, 2008-10-10 12:14:54
figure	[Figure:379257] /figures/DrosEGFRA09.jpg
input	[Complex:379157] cSPI/cGRK/cKRN/VN:Phospho EGFR dimer [plasma membrane] [Drosophila melanogaster] [EntityWithAccessionedSequence:379149] SHC [cytosol] [Drosophila melanogaster]
literatureReference	[LiteratureReference:379168] The Drosophila SHC adaptor protein is required for signaling by a subset of receptor tyrosine kinases [LiteratureReference:379239] A Drosophila shc gene product is implicated in signaling by the DER receptor tyrosine kinase
modified	[InstanceEdit:386963] Williams, MG, 2008-11-27 15:33:38 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9010639] D'Eustachio, Peter, 2017-06-27
name	SHC binds to phosphorylated EGFR
output	[Complex:379121] cSPI/cGRK/cKRN/VN:Phospho EGFR dimer:SHC [plasma membrane] [Drosophila melanogaster]
precedingEvent	[Reaction:379169] EGFR complex dimer autophosphorylates [Drosophila melanogaster] [Reaction:379091] EGFR complex dimerises [Drosophila melanogaster]
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8919926] R-DME-379166.1
summation	[Summation:379156] Shc adaptor protein (SHC) contains an N-terminal phosphotyro...
(hasEvent)	[Pathway:379236] Assembly of the EGFR complex [Drosophila melanogaster]
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