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Details on Person TP53 binds the CDKN1A promoter

Class:IdReaction:3786258
_displayNameTP53 binds the CDKN1A promoter
_doReleaseTRUE
_timestamp2017-02-22 09:42:53
authored[InstanceEdit:3900006] Orlic-Milacic, M, 2013-07-15
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:3786254] Orlic-Milacic, M, 2013-07-04
edited[InstanceEdit:3901124] D'Eustachio, P, 2013-07-15
[InstanceEdit:4542306] Matthews, L, 2013-07-15
input[EntityWithAccessionedSequence:3786256] CDKN1A gene [nucleoplasm] [Homo sapiens]
[Complex:349474] p-S15-TP53 Tetramer [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:69405] WAF1, a potential mediator of p53 tumor suppression.
[LiteratureReference:3785780] p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
modified[InstanceEdit:3788635] Orlic-Milacic, M, 2013-07-04
[InstanceEdit:4415004] Orlic-Milacic, M, 2013-08-23
[InstanceEdit:4416363] Orlic-Milacic, M, 2013-08-26
[InstanceEdit:4420304] Orlic-Milacic, M, 2013-09-03
[InstanceEdit:4420306] Orlic-Milacic, M, 2013-09-03
[InstanceEdit:4542310] Orlic-Milacic, M, 2013-09-04
[InstanceEdit:6792785] Orlic-Milacic, Marija, 2015-08-27
[InstanceEdit:6799324] Orlic-Milacic, Marija, 2015-09-23
[InstanceEdit:6799335] Orlic-Milacic, Marija, 2015-09-24
[InstanceEdit:6803268] Orlic-Milacic, Marija, 2015-10-05
[InstanceEdit:6810439] Orlic-Milacic, Marija, 2015-11-17
[InstanceEdit:8979169] Orlic-Milacic, Marija, 2017-02-22
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameTP53 binds the CDKN1A promoter
output[Complex:3786257] p-S15-TP53 Tetramer:CDKN1A Gene [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2013-09-18
reviewed[InstanceEdit:4542303] Samarajiwa, Shamith, 2013-09-03
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:4545223] R-HSA-3786258.5
summation[Summation:3786259] TP53 (p53), stabilized by ATM-mediated phosphorylation on S1...
(hasEvent)[Pathway:2559586] DNA Damage/Telomere Stress Induced Senescence [Homo sapiens]
(precedingEvent)[Reaction:4647593] EP400 binds CDKN1A promoter [Homo sapiens]
[BlackBoxEvent:4647613] Transcriptional activation of CDKN1A by TP53 is inhibited by EP400 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9783968] Update Tracker - [Reaction:3786258] TP53 binds the CDKN1A promoter - v55:[modifyText]
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No pathways have been reviewed or authored by TP53 binds the CDKN1A promoter (3786258)