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Details on Person CDKN1A gene [nucleoplasm]

Class:Id	EntityWithAccessionedSequence:3786256
_displayName	CDKN1A gene [nucleoplasm]
_timestamp	2016-06-30 15:47:00
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3786254] Orlic-Milacic, M, 2013-07-04
endCoordinate	-1
modified	[InstanceEdit:8878181] Orlic-Milacic, Marija, 2016-06-30
name	CDKN1A gene p21 gene WAF1 gene CIP1 gene
referenceEntity	[ReferenceDNASequence:3786255] ENSEMBL:ENSG00000124762 CDKN1A [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:4545827] R-HSA-3786256.2
startCoordinate	1
(hasComponent)	[Complex:3786257] p-S15-TP53 Tetramer:CDKN1A Gene [nucleoplasm] [Homo sapiens] [Complex:6803802] p-S15,S20-TP53 Tetramer:ZNF385A:CDKN1A Gene [nucleoplasm] [Homo sapiens] [Complex:8865245] TFAP2A homodimer:CDKN1A gene [nucleoplasm] [Homo sapiens] [Complex:8865282] TFAP2C homodimer:MYC:KDM5B:CDKN1A gene [nucleoplasm] [Homo sapiens] [Complex:8878180] RUNX3:p-2S-SMAD3:p-2S-SMAD3:SMAD4:CDKN1A gene [nucleoplasm] [Homo sapiens] [Complex:9008444] (p-S451-RUNX2:CBFB,RUNX2:CBFB,RUNX2:HDAC6):CDKN1A gene [nucleoplasm] [Homo sapiens] [Complex:9617982] FOXO1,FOXO3,FOXO4:CDKN1A gene [nucleoplasm] [Homo sapiens] [Complex:9618005] FOXO3,(FOXO1,FOXO4):p-2S-SMAD2/3:SMAD4:CDKN1A gene [nucleoplasm] [Homo sapiens] [Complex:9698036] p-STAT5:CDKN1A gene [nucleoplasm] [Homo sapiens] [Complex:9825860] MITF-M dimer:CDKN1A gene [nucleoplasm] [Homo sapiens] List all 12 refering instances
(hasMember)	[CandidateSet:5628838] CDKN1A,MDM2,SERPINE1,TIGAR,TNFRSF10C,NDRG1, PYCARD, TRIM22 Genes [nucleoplasm] [Homo sapiens] [DefinedSet:6790033] STAT3-upregulated genes for cytosolic proteins [nucleoplasm] [Homo sapiens]
(input)	[Reaction:3786258] TP53 binds the CDKN1A promoter [Homo sapiens] [BlackBoxEvent:4647613] Transcriptional activation of CDKN1A by TP53 is inhibited by EP400 [Homo sapiens] [BlackBoxEvent:6803388] TP53 stimulates CDKN1A (p21) transcription [Homo sapiens] [Reaction:6803801] TP53 in complex with ZNF385A binds the CDKN1A promoter [Homo sapiens] [Reaction:8865244] TFAP2A homodimer binds CDKN1A (p21) gene [Homo sapiens] [BlackBoxEvent:8865256] CDKN1A gene expression is stimulated by TFAP2A and repressed by TFAP2C [Homo sapiens] [Reaction:8865280] TFAP2C homodimer binds the CDKN1A (p21) gene promoter [Homo sapiens] [BlackBoxEvent:8878130] CDKN1A (p21) gene expression is positively regulated by RUNX3 and ZFHX3 [Homo sapiens] [Reaction:8878178] The complex of RUNX3, SMAD3 and SMAD4 binds the CDKN1A gene promoter [Homo sapiens] [BlackBoxEvent:8878186] CDKN1A gene expression is synergistically activated by RUNX3, SMAD3 and SMAD4 [Homo sapiens] List all 22 refering instances
(replacementInstances)	[_Deleted:9008449] Deletion of instance: 8948447
(updatedInstance)	[_UpdateTracker:9894986] Update Tracker - [EntityWithAccessionedSequence:3786256] CDKN1A gene [nucleoplasm] - v58:[modifyName]
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No pathways have been reviewed or authored by CDKN1A gene [nucleoplasm] (3786256)