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Details on Person EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex
Class:Id Reaction:3781001
_displayName EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex
_doRelease TRUE
_timestamp 2024-12-11 21:03:46
authored [InstanceEdit:3907318] D'Eustachio, P, 2013-07-19
catalystActivity [CatalystActivity:9931456] protein-macromolecule adaptor activity of PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol]
catalystActivityReference [CatalystActivityReference:9931462] protein-macromolecule adaptor activity of PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol] Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)
compartment [Compartment:70101] cytosol
created [InstanceEdit:3781010] D'Eustachio, P, 2013-06-27
input [Complex:3777093] PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol] [Homo sapiens] [Complex:6805697] EPM2A dimer [cytosol] [Homo sapiens]
internalReviewed [InstanceEdit:9931477] D'Eustachio, Peter, 2024-12-11
isChimeric FALSE
literatureReference [LiteratureReference:3777107] Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)
modified [InstanceEdit:3781026] D'Eustachio, P, 2013-06-27 [InstanceEdit:3907319] D'Eustachio, P, 2013-07-19 [InstanceEdit:4006080] D'Eustachio, P, 2013-07-26 [InstanceEdit:5333094] D'Eustachio, Peter, 2014-02-18 [InstanceEdit:6805696] D'Eustachio, Peter, 2015-10-20 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9931474] D'Eustachio, Peter, 2024-12-11 [InstanceEdit:9931476] D'Eustachio, Peter, 2024-12-11
name EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex
output [Complex:3780999] EPM2A:PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol] [Homo sapiens]
precedingEvent
previousReviewStatus [ReviewStatus:9821384] two stars
releaseDate 2013-09-18
reviewed [InstanceEdit:5333091] Pederson, Bart, 2014-02-18 [InstanceEdit:4006079] Jassal, B, 2013-07-26
reviewStatus [ReviewStatus:9821385] four stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:4545258] R-HSA-3781001.5
structureModified [InstanceEdit:9931474] D'Eustachio, Peter, 2024-12-11
summation [Summation:3781007] EPM2A (laforin) dimer binds to the PPP1R3C:phosphoglycogen-G...
(hasEvent) [Pathway:3322077] Glycogen synthesis [Homo sapiens]
(precedingEvent) [Reaction:3781018] EPM2A dimer dephosphorylates phosphoglycogen-GYG1 [Homo sapiens]
(updatedInstance) [_UpdateTracker:9783773] Update Tracker - [Reaction:3781001] EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex - v55:[add_removeInput, modifyText] [_UpdateTracker:9939662] Update Tracker - [Reaction:3781001] EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex - v92:[removeCatalystActivity]
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