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Details on Person PDK1 further phosphorylates, activates and dissociates from S6K1

Class:IdReaction:377430
_displayNamePDK1 further phosphorylates, activates and dissociates from S6K1
_timestamp2016-07-15 23:50:17
authored[InstanceEdit:386955] Williams, MG, 2008-09-08 16:49:12
catalystActivity[CatalystActivity:377328] protein serine/threonine kinase activity of PDPK1 [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:377173] Williams, MG, 2008-09-12 10:01:25
figure[Figure:376903] /figures/ADrosINRA34.jpg
input[Complex:377408] PDK1:PIP3:Phospho S6K1 [plasma membrane] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:376958] 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro
[LiteratureReference:377314] A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation
modified[InstanceEdit:386961] Williams, MG, 2008-11-27 15:11:43
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:8879177] Wu, G, 2016-07-15
namePDK1 further phosphorylates, activates and dissociates from S6K1
output[Complex:377179] PDPK1:PIP3 [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:377418] Phospho (2 sites) S6K1 [cytosol] [Rattus norvegicus]
[SimpleEntity:29370] ADP [cytosol]
species[Species:48887] Homo sapiens
[Species:48895] Rattus norvegicus
stableIdentifier[StableIdentifier:8916445] R-NUL-377430.1
summation[Summation:377189] 3-phosphoinositide-dependent protein kinase 1 (PDK1) phospho...
(hasEvent)[Pathway:377009] Insulin Receptor pathway - Inferred Events
(inferredFrom)[Reaction:377013] PK61C further phosphorylates, activates and dissociates from S6K [Drosophila melanogaster]
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No pathways have been reviewed or authored by PDK1 further phosphorylates, activates and dissociates from S6K1 (377430)