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Details on Person Rheb:GTP complex binds to TSC2:TSC1 complex

Class:Id	Reaction:377373
_displayName	Rheb:GTP complex binds to TSC2:TSC1 complex
_timestamp	2016-07-15 23:50:43
authored	[InstanceEdit:386955] Williams, MG, 2008-09-08 16:49:12
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:377173] Williams, MG, 2008-09-12 10:01:25
figure	[Figure:376915] /figures/ADrosINRA47.jpg
input	[Complex:377052] Rheb:GTP [plasma membrane] [Homo sapiens] [Complex:165175] TSC1:TSC2 [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:377126] Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner [LiteratureReference:377025] Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity [LiteratureReference:377385] The GTPase-activating protein Rap1GAP uses a catalytic asparagine [LiteratureReference:377217] Structural basis for the unique biological function of small GTPase RHEB
modified	[InstanceEdit:386962] Williams, MG, 2008-11-27 15:15:51 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8879177] Wu, G, 2016-07-15
name	Rheb:GTP complex binds to TSC2:TSC1 complex
output	[Complex:377149] Rheb:GTP:TSC2:TSC1 [plasma membrane] [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8926810] R-HSA-377373.1
summation	[Summation:377105] TSC2 in the Tuberous Sclerosis Complex binds to active Rheb ...
(hasEvent)	[Pathway:377009] Insulin Receptor pathway - Inferred Events
(inferredFrom)	[Reaction:377144] RHEB:GTP complex binds to GIG:TSC1 complex [Drosophila melanogaster]
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No pathways have been reviewed or authored by Rheb:GTP complex binds to TSC2:TSC1 complex (377373)