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Details on Person Phosphorylated PRAS40 dissociates from activated mTOR

Class:IdReaction:377355
_displayNamePhosphorylated PRAS40 dissociates from activated mTOR
_timestamp2016-07-15 23:49:17
authored[InstanceEdit:386955] Williams, MG, 2008-09-08 16:49:12
compartment[Compartment:70101] cytosol
created[InstanceEdit:377173] Williams, MG, 2008-09-12 10:01:25
figure[Figure:376905] /figures/ADrosINRA23.jpg
input[Complex:377298] mLST8:mTOR:Raptor:Phospho (3 sites) PRAS40 [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:377097] PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding
[LiteratureReference:377225] The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1
[LiteratureReference:377103] Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation
modified[InstanceEdit:386962] Williams, MG, 2008-11-27 15:15:51
[InstanceEdit:8879177] Wu, G, 2016-07-15
namePhosphorylated PRAS40 dissociates from activated mTOR
output[Complex:377220] mLST8:mTOR:Raptor [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:377076] p-S183,S221,T246-AKT1S1 [cytosol] [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8890974] R-HSA-377355.1
summation[Summation:377214] After Proline Rich Akt Substrate 40 kDa (PRAS40) is phosphor...
(hasEvent)[Pathway:377009] Insulin Receptor pathway - Inferred Events
(inferredFrom)[Reaction:377012] Phosphorylated L dissociates from activated TOR [Drosophila melanogaster]
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