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Details on Person Phosphorylation of the eukaryotic intiation factor 4E bindin...
| Class:Id | Summation:377330 |
|---|---|
| _displayName | Phosphorylation of the eukaryotic intiation factor 4E bindin... |
| _timestamp | 2008-09-12 10:28:11 |
| created | [InstanceEdit:377173] Williams, MG, 2008-09-12 10:01:25 |
| text | Phosphorylation of the eukaryotic intiation factor 4E binding protein orthologue (THOR) promotes its dissociation from EIF-4E bound to the mRNA 7-methylguanosine cap structure, allowing for recruitment of EIF-4G and EIF-4A. These latter two along with EIF-4E are often referred to as the EIF4F complex. EIF3 complex, EIF1, EIF1A, 40S ribosomal subunits, and the ternary complex (EIF2:Met-tRNA:GTP) are also recruited to the cap, resulting in the assembly of the translation preinitiation complex (PIC). |
| (summation) | [Reaction:377415] Formation of the preinitiation complex [Drosophila melanogaster] |
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No pathways have been reviewed or authored by Phosphorylation of the eukaryotic intiation factor 4E bindin... (377330)
