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Details on Person Activated AKT1 phosphorylates FOXO

Class:Id	Reaction:377302
_displayName	Activated AKT1 phosphorylates FOXO
_doRelease	FALSE
_timestamp	2017-06-27 17:34:24
authored	[InstanceEdit:386955] Williams, MG, 2008-09-08 16:49:12
catalystActivity	[CatalystActivity:377165] protein serine/threonine kinase activity of Phospho (2 sites) AKT1 [plasma membrane]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:377173] Williams, MG, 2008-09-12 10:01:25
figure	[Figure:376925] /figures/ADrosINRA54.jpg
input	[EntityWithAccessionedSequence:110472] FOXO [cytosol] [Drosophila melanogaster] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:377336] Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway
modified	[InstanceEdit:386957] Williams, MG, 2008-11-27 14:37:44 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9010639] D'Eustachio, Peter, 2017-06-27
name	Activated AKT1 phosphorylates FOXO
output	[EntityWithAccessionedSequence:377054] Phospho FOXO [cytosol] [Drosophila melanogaster] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:377142] PK61C further phosphorylates and fully activates AKT1 [Drosophila melanogaster] [Reaction:377209] TOR phosphorylates AKT1 [Drosophila melanogaster] [Reaction:377444] Activated TOR phosphorylates AKT1 [Drosophila melanogaster] [Reaction:377045] PP2A dephosphorylates AKT1 [Drosophila melanogaster]
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8905565] R-DME-377302.1
summation	[Summation:377091] In favourable growth conditions, where nutrients are availab...
(hasEvent)	[Pathway:377093] FOXO dependent transcription activation [Drosophila melanogaster]
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No pathways have been reviewed or authored by Activated AKT1 phosphorylates FOXO (377302)