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Details on Person TOR phosphorylates AKT1

Class:IdReaction:377209
_displayNameTOR phosphorylates AKT1
_doReleaseFALSE
_timestamp2017-06-27 17:38:39
authored[InstanceEdit:386955] Williams, MG, 2008-09-08 16:49:12
catalystActivity[CatalystActivity:376997] protein serine/threonine kinase activity of TOR [cytosol]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:377173] Williams, MG, 2008-09-12 10:01:25
figure[Figure:376909] /figures/ADrosINRA09.jpg
input[Complex:377256] AKT1:PIP3 [plasma membrane] [Drosophila melanogaster]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:199373] Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
[LiteratureReference:377301] Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity
[LiteratureReference:377194] Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth
modified[InstanceEdit:386963] Williams, MG, 2008-11-27 15:33:38
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:9010639] D'Eustachio, Peter, 2017-06-27
nameTOR phosphorylates AKT1
output[Complex:377081] Phospho AKT1:PIP3 [plasma membrane] [Drosophila melanogaster]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
species[Species:56210] Drosophila melanogaster
stableIdentifier[StableIdentifier:8921731] R-DME-377209.1
summation[Summation:376991] Target of rapamycin (TOR) kinase in complex with Rapamycin-i...
(hasEvent)[Pathway:377038] Regulation of AKT1 [Drosophila melanogaster]
(precedingEvent)[Reaction:377142] PK61C further phosphorylates and fully activates AKT1 [Drosophila melanogaster]
[Reaction:377274] PHLPP dephosphorylates AKT1 [Drosophila melanogaster]
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No pathways have been reviewed or authored by TOR phosphorylates AKT1 (377209)