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Query author contributions in Reactome
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Details on Person UniProt:Q9VN25 eIF3a
Class:Id
ReferenceGeneProduct:377138
_chainChangeLog
chain:1-1140 added on Sat February 7 2015
_displayName
UniProt:Q9VN25 eIF3a
_timestamp
2025-08-15 22:16:59
chain
chain:1-1140
checksum
E249F68B8861B6DC
comment
FUNCTION RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.SUBUNIT Component of the eukaryotic translation initiation factor 3 (eIF-3) complex (By similarity) (PubMed:17392269). The eIF-3 complex interacts with pix (By similarity) (PubMed:17392269).SUBCELLULAR LOCATION Belongs to the eIF-3 subunit A family.SEQUENCE CAUTION Truncated N-terminus.
