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Details on Person PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding

Class:IdLiteratureReference:377097
_displayNamePRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding
_timestamp2008-09-12 10:25:20
author[Person:209936] Wang, L
[Person:377151] Harris, TE
[Person:200142] Roth, RA
[Person:377152] Lawrence JC, Jr
created[InstanceEdit:377173] Williams, MG, 2008-09-12 10:01:25
journalJ Biol Chem
pages20036-44
pubMedIdentifier17510057
titlePRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding
volume282
year2007
(literatureReference)[Reaction:377355] Phosphorylated PRAS40 dissociates from activated mTOR [Homo sapiens]
[Reaction:5672843] AKT1S1 (PRAS40) binds mTORC1 [Homo sapiens]
[Summation:5672784] AKT1S1 (PRAS40, proline-rich AKT/PKB substrate 40 kDa) is an...
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