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Details on Person Activated S6K1 phosphorylates the 40S ribosomal subunits

Class:IdReaction:376956
_displayNameActivated S6K1 phosphorylates the 40S ribosomal subunits
_timestamp2016-07-15 23:49:44
authored[InstanceEdit:386955] Williams, MG, 2008-09-08 16:49:12
catalystActivity[CatalystActivity:377043] protein serine/threonine kinase activity of Phospho (2 sites) S6K1 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:377173] Williams, MG, 2008-09-12 10:01:25
figure[Figure:376914] /figures/ADrosINRA39.jpg
input[Complex:377130] mLST8:mTOR:Raptor:eIF4E:eIF3:eIF4G:eIF1:eIF1A:eIF5:eIF4A:40S ribosomal complex:ternary complex [cytosol] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:377044] mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
modified[InstanceEdit:386957] Williams, MG, 2008-11-27 14:37:44
[InstanceEdit:8879177] Wu, G, 2016-07-15
nameActivated S6K1 phosphorylates the 40S ribosomal subunits
output[Complex:377365] mLST8:mTOR:Raptor:eIF4E:eIF3:eIF4G:eIF1:eIF1A:eIF5:eIF4A:Phospho 40S ribosomal complex:ternary complex [cytosol] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
species[Species:48887] Homo sapiens
[Species:48895] Rattus norvegicus
stableIdentifier[StableIdentifier:8902585] R-NUL-376956.1
summation[Summation:377064] The S6 subunit of the 40S ribosome complex (RPS6) is phospho...
(hasEvent)[Pathway:377009] Insulin Receptor pathway - Inferred Events
(inferredFrom)[Reaction:377273] Activated S6K phosphorylates the 40S ribosomal subunits [Drosophila melanogaster]
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