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Details on Person Vamp8 associated secretory vesicle to plasma membrane transport
Class:Id Reaction:376364
_displayName Vamp8 associated secretory vesicle to plasma membrane transport
_doRelease TRUE
_timestamp 2018-12-20 21:01:00
authored [InstanceEdit:434217] Gillespie, ME, 2009-08-27
catalystActivity [CatalystActivity:376375] SNARE binding activity of Vamp8:SNAP23:Syn4 Secretory granule docking and fusion complex [plasma membrane]
compartment [Compartment:70101] cytosol
created [InstanceEdit:376371] Gillespie, ME, 2008-09-06 05:38:37
input [EntityWithAccessionedSequence:376345] SNAP23 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:181519] STX4 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:376368] VAMP8 [secretory granule membrane] [Homo sapiens]
literatureReference [LiteratureReference:8984246] Escherichia coli exposure inhibits exocytic SNARE-mediated membrane fusion in mast cells [LiteratureReference:8863956] Phosphorylation of SNAP-23 by IkappaB kinase 2 regulates mast cell degranulation [LiteratureReference:8984232] Allergen-sensitization increases mast-cell expression of the exocytotic proteins SNAP-23 and syntaxin 4, which are involved in histamine secretion [LiteratureReference:8984223] Ternary SNARE complexes are enriched in lipid rafts during mast cell exocytosis [LiteratureReference:8984252] Relocation of the t-SNARE SNAP-23 from lamellipodia-like cell surface projections regulates compound exocytosis in mast cells
modified [InstanceEdit:376377] Gillespie, ME, 2008-09-06 05:39:36 [InstanceEdit:376430] Gillespie, ME, 2008-09-08 03:19:22 [InstanceEdit:381828] Gillespie, ME, 2008-11-20 17:51:26 [InstanceEdit:425650] Gillespie, ME, 2009-06-05 [InstanceEdit:433008] Gillespie, ME, 2009-08-20 [InstanceEdit:433043] Gillespie, ME, 2009-08-20 [InstanceEdit:434285] Gillespie, ME, 2009-08-27 [InstanceEdit:434871] Gillespie, ME, 2009-09-03 [InstanceEdit:435035] Gillespie, ME, 2009-09-04 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:8984258] Duenas, Corina, 2017-04-05 [InstanceEdit:9632728] Gillespie, Marc E, 2018-12-20 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Vamp8 associated secretory vesicle to plasma membrane transport
output [EntityWithAccessionedSequence:376345] SNAP23 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:181519] STX4 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:376365] VAMP8 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate 2008-09-30
reviewed [InstanceEdit:165091] Rush, MG, 2008-01-11 00:00:00
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:377945] R-HSA-376364.5
summation [Summation:376366] The vamp8 associated vesicle docks and fuses with the plasma...
(hasEvent) [Pathway:199992] trans-Golgi Network Vesicle Budding [Homo sapiens]
(updatedInstance) [_UpdateTracker:9780983] Update Tracker - [Reaction:376364] Vamp8 associated secretory vesicle to plasma membrane transport - v61:[addLiteratureReference] [_UpdateTracker:9791685] Update Tracker - [Reaction:376364] Vamp8 associated secretory vesicle to plasma membrane transport - v27:[add_removeInput, add_removeOutput]
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