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Details on Person SLC7A10-mediated uptake of small neutral amino acids

Class:Id	Reaction:376200
_displayName	SLC7A10-mediated uptake of small neutral amino acids
_doRelease	TRUE
_timestamp	2025-08-14 07:23:19
authored	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
catalystActivity	[CatalystActivity:376185] amino acid transmembrane transporter activity of SLC7A10:SLC3A2 heterodimer [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:376197] D'Eustachio, P, 2008-09-05 22:30:03
edited	[InstanceEdit:377486] D'Eustachio, P, 2008-09-12 21:44:24
input	[DefinedSet:376201] ligands of SLC7A10 [extracellular region]
literatureReference	[LiteratureReference:376199] Cloning and characterization of a human brain Na(+)-independent transporter for small neutral amino acids that transports D-serine with high affinity
modified	[InstanceEdit:376202] D'Eustachio, P, 2008-09-05 22:30:29 [InstanceEdit:376423] D'Eustachio, P, 2008-09-06 21:21:04 [InstanceEdit:377487] D'Eustachio, P, 2008-09-12 21:45:58 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9963210] Stephan, Ralf, 2025-08-13 [InstanceEdit:9963282] Stephan, Ralf, 2025-08-14
name	SLC7A10-mediated uptake of small neutral amino acids
negativePrecedingEvent	[NegativePrecedingEvent:9963216] Futile Cycle: SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine [NegativePrecedingEvent:9963205] Futile Cycle: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine [NegativePrecedingEvent:9963287] Futile Cycle: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine [NegativePrecedingEvent:9963286] Futile Cycle: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine [NegativePrecedingEvent:9963320] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane
output	[DefinedSet:376196] ligands of SLC7A10 [cytosol]
releaseDate	2008-09-30
reviewed	[InstanceEdit:352498] Jassal, Bijay, 2008-06-03
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:377975] R-HSA-376200.3
summation	[Summation:376187] SLC7A10, complexed with SLC3A2 in the plasma membrane, media...
(hasEvent)	[Pathway:352230] Amino acid transport across the plasma membrane [Homo sapiens]
(precedingEvent)	[NegativePrecedingEvent:9963373] Futile Cycle: SLC7A10-mediated uptake of small neutral amino acids [NegativePrecedingEvent:9963382] Futile Cycle: SLC7A10-mediated uptake of small neutral amino acids [NegativePrecedingEvent:9963383] Futile Cycle: SLC7A10-mediated uptake of small neutral amino acids [NegativePrecedingEvent:9963401] Futile Cycle: SLC7A10-mediated uptake of small neutral amino acids [NegativePrecedingEvent:9963422] Futile Cycle: SLC7A10-mediated uptake of small neutral amino acids
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