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Details on Person Proteolytic processing of SLIT

Class:IdReaction:376149
_displayNameProteolytic processing of SLIT
_doReleaseTRUE
_timestamp2018-03-13 16:19:56
authored[InstanceEdit:376175] Garapati, P V, 2008-09-05 06:02:05
catalystActivity[CatalystActivity:428539] peptidase activity of Unidentified protease [cytosol]
compartment[Compartment:876] plasma membrane
created[InstanceEdit:376150] Garapati, P V, 2008-09-04 23:27:04
edited[InstanceEdit:376175] Garapati, P V, 2008-09-05 06:02:05
[InstanceEdit:9009839] Orlic-Milacic, Marija, 2017-06-23
input[EntityWithAccessionedSequence:375997] SLIT2 [extracellular region] [Homo sapiens]
literatureReference[LiteratureReference:375922] Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance
[LiteratureReference:428397] Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching
modified[InstanceEdit:428538] Garapati, P V, 2009-07-06
[InstanceEdit:434971] Garapati, P V, 2009-09-04
[InstanceEdit:9009840] Orlic-Milacic, Marija, 2017-06-23
[InstanceEdit:9014892] Orlic-Milacic, Marija, 2017-08-04
[InstanceEdit:9038671] Orlic-Milacic, Marija, 2018-03-13
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameProteolytic processing of SLIT
output[EntityWithAccessionedSequence:426412] SLIT2(1122-1529) [extracellular region] [Homo sapiens]
[EntityWithAccessionedSequence:426409] SLIT2(31-1121) [extracellular region] [Homo sapiens]
precedingEvent
releaseDate2009-09-30
reviewed[InstanceEdit:434966] Kidd, T, 2009-08-18
[InstanceEdit:9014887] Jaworski, Alexander, 2017-07-31
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1105553] R-HSA-376149.4
summation[Summation:375914] The full length SLIT proteins are secreted and, when not bou...
(hasEvent)[Pathway:376176] Signaling by ROBO receptors [Homo sapiens]
(precedingEvent)[Reaction:428518] Glypican-1 (GPC1) binds SLIT2 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9777307] Update Tracker - [Reaction:376149] Proteolytic processing of SLIT - v72:[modifyText]
[_UpdateTracker:9778975] Update Tracker - [Reaction:376149] Proteolytic processing of SLIT - v66:[modifyText]
[_UpdateTracker:9780855] Update Tracker - [Reaction:376149] Proteolytic processing of SLIT - v62:[modifyText]
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