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Details on Person Interaction of ABL with ROBO1:SLIT2

Class:Id	Reaction:376141
_displayName	Interaction of ABL with ROBO1:SLIT2
_doRelease	TRUE
_timestamp	2017-11-17 16:24:09
authored	[InstanceEdit:376175] Garapati, P V, 2008-09-05 06:02:05
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:376144] Garapati, P V, 2008-09-04 23:26:18
edited	[InstanceEdit:376175] Garapati, P V, 2008-09-05 06:02:05 [InstanceEdit:9010186] Orlic-Milacic, Marija, 2017-06-26
input	[DefinedSet:376002] ABL [cytosol] [Homo sapiens] [Complex:390371] ROBO1:SLIT2 [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:375873] Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor
modified	[InstanceEdit:428538] Garapati, P V, 2009-07-06 [InstanceEdit:428881] Garapati, P V, 2009-07-10 [InstanceEdit:434971] Garapati, P V, 2009-09-04 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:9010158] Orlic-Milacic, Marija, 2017-06-26 [InstanceEdit:9010187] Orlic-Milacic, Marija, 2017-06-26 [InstanceEdit:9014895] Orlic-Milacic, Marija, 2017-08-04 [InstanceEdit:9029384] Orlic-Milacic, Marija, 2017-11-17 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Interaction of ABL with ROBO1:SLIT2
output	[Complex:428873] SLIT2:ROBO1:ABL [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:204364] ROBO1 binds SLIT2 [Homo sapiens] [BlackBoxEvent:9010539] SLIT2 gene expression is stimulated by ISL1 [Homo sapiens] [BlackBoxEvent:9011083] ROBO1 gene expression is inhibited by LHX2 [Homo sapiens]
releaseDate	2009-09-30
reviewed	[InstanceEdit:434966] Kidd, T, 2009-08-18 [InstanceEdit:9014887] Jaworski, Alexander, 2017-07-31
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1105762] R-HSA-376141.4
summation	[Summation:375878] ABL (ABL1 or ABL2) binds directly, via its SH3 domain, to th...
(hasEvent)	[Pathway:428890] Role of ABL in ROBO-SLIT signaling [Homo sapiens]
(precedingEvent)	[Reaction:428883] Recruitment of CAP to ABL [Homo sapiens] [Reaction:428885] Activation of CLASP [Homo sapiens] [Reaction:428888] Phosphorylation of ROBO1 by ABL kinase [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9780512] Update Tracker - [Reaction:376141] Interaction of ABL with ROBO1:SLIT2 - v62:[modifyText]
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No pathways have been reviewed or authored by Interaction of ABL with ROBO1:SLIT2 (376141)