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Details on Person SLIT2 [extracellular region]
Class:Id EntityWithAccessionedSequence:375997
_displayName SLIT2 [extracellular region]
_timestamp 2020-02-03 17:07:19
compartment [Compartment:984] extracellular region
created [InstanceEdit:375994] Garapati, P V, 2008-09-04 23:02:38
endCoordinate 1529
modified [InstanceEdit:425198] Garapati, P V, 2009-06-03 [InstanceEdit:428469] Garapati, P V, 2009-07-06 [InstanceEdit:3632907] Wu, G, 2013-05-28 [InstanceEdit:9010829] Orlic-Milacic, Marija, 2017-06-28 [InstanceEdit:9675211] Orlic-Milacic, Marija, 2020-02-03
name SLIT2 SLIT2(31-1529) Slit homolog 2 protein SLIT2_HUMAN
referenceEntity [ReferenceGeneProduct:101714] UniProt:O94813 SLIT2 [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:1110650] R-HSA-375997.3
startCoordinate 31
(entityOnOtherCell) [Complex:390377] ROBO4:Slit2 [plasma membrane] [Homo sapiens] [Reaction:204364] ROBO1 binds SLIT2 [Homo sapiens] [Reaction:428518] Glypican-1 (GPC1) binds SLIT2 [Homo sapiens] [Reaction:428882] Slit-2 binds Robo4 [Homo sapiens]
(hasComponent) [Complex:376029] ROBO:Slit2 [plasma membrane] [Homo sapiens] [Complex:390371] ROBO1:SLIT2 [plasma membrane] [Homo sapiens] [Complex:390373] ROBO3:Slit2 [plasma membrane] [Homo sapiens] [Complex:390377] ROBO4:Slit2 [plasma membrane] [Homo sapiens] [Complex:390379] ROBO2:Slit2 [plasma membrane] [Homo sapiens] [Complex:428488] Robo1:Slit2 [plasma membrane] [Rattus norvegicus] [Complex:428499] p-Y1073-ROBO1:SLIT2 [plasma membrane] [Homo sapiens] [Complex:9010869] SLIT2:Dystroglycan [plasma membrane] [Homo sapiens] [Complex:9010899] ROBO2:SLIT2 [plasma membrane] [Homo sapiens]
(hasMember) [DefinedSet:390366] SLIT [extracellular region] [Homo sapiens] [CandidateSet:9010822] SLIT2,(SLIT3) [extracellular region] [Homo sapiens] [DefinedSet:9014805] SLIT2,SLIT2 cleavage fragments [extracellular region] [Homo sapiens]
(input) [Reaction:204364] ROBO1 binds SLIT2 [Homo sapiens] [Reaction:376149] Proteolytic processing of SLIT [Homo sapiens] [Reaction:428882] Slit-2 binds Robo4 [Homo sapiens] [Reaction:9010872] SLIT2 binds Dystroglycan [Homo sapiens] [Reaction:9010898] ROBO2 binds SLIT2 [Homo sapiens]
(output) [BlackBoxEvent:9010539] SLIT2 gene expression is stimulated by ISL1 [Homo sapiens]
(updatedInstance) [_UpdateTracker:9881321] Update Tracker - [EntityWithAccessionedSequence:375997] SLIT2 [extracellular region] - v45:[addName] [_UpdateTracker:9901184] Update Tracker - [EntityWithAccessionedSequence:375997] SLIT2 [extracellular region] - v72:[add_removeCompartment]
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Pathways
No pathways have been reviewed or authored by SLIT2 [extracellular region] (375997)