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Details on Person MALT1 mediates NF-kappaB activation by facilitating Lys-63 p...
| Class:Id | Summation:375911 |
|---|---|
| _displayName | MALT1 mediates NF-kappaB activation by facilitating Lys-63 p... |
| _timestamp | 2008-09-04 22:56:13 |
| created | [InstanceEdit:375910] Garapati, P V, 2008-09-04 22:55:57 |
| text | MALT1 mediates NF-kappaB activation by facilitating Lys-63 polyubiquitination of NEMO, which is an essential regulatory subunit of the IKK complex. MALT1 contains two Ig-like domains and a death domain at its N terminus, and a region that weakly resembles the catalytic domain of caspases at its C terminus. MALT1 interacts with BCL10 and TRAF6 to mediates NF-kappaB signaling through the BCL10-MALT1-TRAF6-TAK1 cascade. |
| (summation) | [Pathway:375167] MALT-1 interactions [Homo sapiens] |
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No pathways have been reviewed or authored by MALT1 mediates NF-kappaB activation by facilitating Lys-63 p... (375911)
