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Details on Person JLP is a scaffold protein for the p38 MAPK pathway. During m...

Class:IdSummation:375891
_displayNameJLP is a scaffold protein for the p38 MAPK pathway. During m...
_timestamp2010-01-19 09:34:14
created[InstanceEdit:375895] Garapati, P V, 2008-09-04 22:55:17
literatureReference[LiteratureReference:375890] Activation of p38alpha/beta MAPK in myogenesis via binding of the scaffold protein JLP to the cell surface protein Cdo
modified[InstanceEdit:448801] Garapati, P V, 2009-11-26
[InstanceEdit:449212] Garapati, P V, 2009-12-02
[InstanceEdit:453163] Garapati, P V, 2010-01-19
textJLP is a scaffold protein for the p38 MAPK pathway. During myogenic differentiation JLP binds the intracellular region of CDO which in turn binds p38 leading to p38 activation. The major CDO-binding region of JLP resides between amino acids 465-647.
(summation)[Reaction:376117] JLP interacts with CDO complex [Homo sapiens]
[Reaction:448954] JLP interacts with CDO complex [Mus musculus]
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