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Details on Person SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol
Class:Id Reaction:375487 _displayName SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol _doRelease TRUE _timestamp 2025-08-14 07:45:10 authored [InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30 catalystActivity [CatalystActivity:375486] amino acid transmembrane transporter activity of SLC6A14 [plasma membrane] compartment [Compartment:876] plasma membrane created [InstanceEdit:375485] D'Eustachio, P, 2008-08-29 20:22:39 crossReference [DatabaseIdentifier:9956815] RHEA:70692 [DatabaseIdentifier:9956816] RHEA:71280 [DatabaseIdentifier:9956827] RHEA:71288 [DatabaseIdentifier:9956821] RHEA:71300 [DatabaseIdentifier:9956824] RHEA:71304 [DatabaseIdentifier:9956830] RHEA:71308 [DatabaseIdentifier:9956836] RHEA:71312 [DatabaseIdentifier:9956845] RHEA:71316 [DatabaseIdentifier:9956825] RHEA:71320 [DatabaseIdentifier:9956814] RHEA:71336 [DatabaseIdentifier:9956817] RHEA:71344 [DatabaseIdentifier:9956839] RHEA:71348 [DatabaseIdentifier:9956812] RHEA:71248 edited [InstanceEdit:377486] D'Eustachio, P, 2008-09-12 21:44:24 input [DefinedSet:375468] SLC6A14 ligands [extracellular region] [SimpleEntity:188972] Cl- [extracellular region] [SimpleEntity:74113] Na+ [extracellular region] [SimpleEntity:74113] Na+ [extracellular region] literatureReference [LiteratureReference:375491] Cloning and functional expression of a human Na(+) and Cl(-)-dependent neutral and cationic amino acid transporter B(0+) [LiteratureReference:375465] Human solute carrier SLC6A14 is the {beta}-alanine carrier modified [InstanceEdit:375492] D'Eustachio, P, 2008-08-29 20:22:58 [InstanceEdit:376423] D'Eustachio, P, 2008-09-06 21:21:04 [InstanceEdit:377487] D'Eustachio, P, 2008-09-12 21:45:58 [InstanceEdit:5659650] Jassal, Bijay, 2014-12-22 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9956833] Stephan, Ralf, 2025-06-14 [InstanceEdit:9963210] Stephan, Ralf, 2025-08-13 [InstanceEdit:9963282] Stephan, Ralf, 2025-08-14 [InstanceEdit:9963370] Stephan, Ralf, 2025-08-14 name SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol negativePrecedingEvent [NegativePrecedingEvent:9963228] Futile Cycle: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine [NegativePrecedingEvent:9963293] Futile Cycle: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine [NegativePrecedingEvent:9963289] Futile Cycle: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine [NegativePrecedingEvent:9963322] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane [NegativePrecedingEvent:9963412] Futile Cycle: SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine [NegativePrecedingEvent:9963420] Futile Cycle: SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane [NegativePrecedingEvent:9963419] Futile Cycle: SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu output [DefinedSet:375459] SLC6A14 ligands [cytosol] [SimpleEntity:352022] Cl- [cytosol] [SimpleEntity:83910] Na+ [cytosol] [SimpleEntity:83910] Na+ [cytosol] precedingEvent
releaseDate 2008-09-30 reviewed [InstanceEdit:352498] Jassal, Bijay, 2008-06-03 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:377926] R-HSA-375487.3 summation [Summation:375476] SLC6A14, associated with the plasma membrane, mediates the u... (hasEvent) [Pathway:352230] Amino acid transport across the plasma membrane [Homo sapiens] [Pathway:442660] SLC-mediated transport of neurotransmitters [Homo sapiens] (normalReaction) [FailedReaction:5659674] Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol [Homo sapiens] (precedingEvent) [NegativePrecedingEvent:9963327] Futile Cycle: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol [NegativePrecedingEvent:9963328] Futile Cycle: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol [NegativePrecedingEvent:9963337] Futile Cycle: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol [NegativePrecedingEvent:9963351] Futile Cycle: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol [NegativePrecedingEvent:9963353] Futile Cycle: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol [NegativePrecedingEvent:9963355] Futile Cycle: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol [NegativePrecedingEvent:9963357] Futile Cycle: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol [NegativePrecedingEvent:9963358] Futile Cycle: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol [NegativePrecedingEvent:9963600] Futile Cycle: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol [Reaction:428625] Vesicular inhibitory amino acid transport [Homo sapiens] (updatedInstance) [_UpdateTracker:9785005] Update Tracker - [Reaction:375487] SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol - v52:[modifyText]
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