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Details on Person SLC6A19 mediates the uptake of neutral amino acids across th...

Class:IdSummation:375461
_displayNameSLC6A19 mediates the uptake of neutral amino acids across th...
_timestamp2015-08-04 13:00:48
created[InstanceEdit:375485] D'Eustachio, P, 2008-08-29 20:22:39
modified[InstanceEdit:375492] D'Eustachio, P, 2008-08-29 20:22:58
[InstanceEdit:5659745] Jassal, Bijay, 2014-12-23
[InstanceEdit:6789777] Jassal, Bijay, 2015-08-04
textSLC6A19 mediates the uptake of neutral amino acids across the plasma membrane. Uptake of an amino acid molecule is accompanied by uptake of a sodium ion. The protein is abundant in cells in the small intestine and kidney. Its deficiency is associated with Hartnup disorder, the failure to take up neutral amino acids efficiently from the gut lumen and to reabsorb them in the proximal kidney tubule (Kleta et al. 2004, Seow et al. 2004).
(summation)[Reaction:375473] SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol [Homo sapiens]
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