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Details on Person SLC36A1-mediated uptake of glycine, proline, and alanine

Class:IdReaction:375417
_displayNameSLC36A1-mediated uptake of glycine, proline, and alanine
_doReleaseTRUE
_timestamp2025-08-14 07:21:51
authored[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
catalystActivity[CatalystActivity:375408] amino acid transmembrane transporter activity of SLC36A1 [plasma membrane]
compartment[Compartment:876] plasma membrane
created[InstanceEdit:375406] D'Eustachio, P, 2008-08-26 22:23:10
crossReference[DatabaseIdentifier:9959415] RHEA:28901
[DatabaseIdentifier:9959414] RHEA:28964
[DatabaseIdentifier:9959416] RHEA:29445
edited[InstanceEdit:377486] D'Eustachio, P, 2008-09-12 21:44:24
input[DefinedSet:375400] ligands of SLC36A1 [extracellular region]
[SimpleEntity:351626] H+ [extracellular region]
literatureReference[LiteratureReference:375412] Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2
modified[InstanceEdit:375422] D'Eustachio, P, 2008-08-26 22:23:33
[InstanceEdit:376423] D'Eustachio, P, 2008-09-06 21:21:04
[InstanceEdit:377487] D'Eustachio, P, 2008-09-12 21:45:58
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9959413] Stephan, Ralf, 2025-06-29
[InstanceEdit:9963210] Stephan, Ralf, 2025-08-13
[InstanceEdit:9963282] Stephan, Ralf, 2025-08-14
nameSLC36A1-mediated uptake of glycine, proline, and alanine
negativePrecedingEvent[NegativePrecedingEvent:9963215] Futile Cycle: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine
[NegativePrecedingEvent:9963212] Futile Cycle: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine
[NegativePrecedingEvent:9963312] Futile Cycle: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine
[NegativePrecedingEvent:9963299] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane
output[DefinedSet:375411] ligands of SLC36A1 [cytosol]
[SimpleEntity:70106] H+ [cytosol]
precedingEvent
releaseDate2008-09-30
reviewed[InstanceEdit:352498] Jassal, Bijay, 2008-06-03
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:377910] R-HSA-375417.3
summation[Summation:375402] SLC36A1 (PAT1), associated with the plasma membrane, mediate...
(hasEvent)[Pathway:352230] Amino acid transport across the plasma membrane [Homo sapiens]
[Pathway:428559] Proton-coupled neutral amino acid transporters [Homo sapiens]
(precedingEvent)[NegativePrecedingEvent:9963285] Futile Cycle: SLC36A1-mediated uptake of glycine, proline, and alanine
[NegativePrecedingEvent:9963294] Futile Cycle: SLC36A1-mediated uptake of glycine, proline, and alanine
[NegativePrecedingEvent:9963326] Futile Cycle: SLC36A1-mediated uptake of glycine, proline, and alanine
[NegativePrecedingEvent:9963339] Futile Cycle: SLC36A1-mediated uptake of glycine, proline, and alanine
[NegativePrecedingEvent:9963340] Futile Cycle: SLC36A1-mediated uptake of glycine, proline, and alanine
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