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Details on Person GFRalpha receptors GFRalpha1 and possibly also GFRalpha2 and...
| Class:Id | Summation:375053 |
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| _displayName | GFRalpha receptors GFRalpha1 and possibly also GFRalpha2 and... |
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| _timestamp | 2009-09-04 08:54:48 |
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| created | [InstanceEdit:375044] Garapati, P V, 2008-08-11 10:27:37 |
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| literatureReference | [LiteratureReference:375010] The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands |
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| modified | [InstanceEdit:420318] Garapati, P V, 2009-05-11 14:08:35
[InstanceEdit:420749] D'Eustachio, P, 2009-05-13 15:09:14
[InstanceEdit:422265] Garapati, P V, 2009-05-27 13:51:08
[InstanceEdit:434893] Garapati, P V, 2009-09-04 |
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| text | GFRalpha receptors GFRalpha1 and possibly also GFRalpha2 and GFRalpha4 subunit of the GDNF (glial cell line-derived neurotrophic factor) receptor interact in cis with NCAM and functions as a coreceptor for GDNF in the absence of RET. The NCAM1-GFRalpha1 interaction down regulates NCAM1-mediated cell adhesion and promotes GDNF-NCAM1 binding. |
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| (summation) | [Reaction:375149] Interaction of NCAM1 with GFRalpha-1 [Homo sapiens]
[Reaction:420383] Interaction of NCAM1 with GFRalpha-1 [Rattus norvegicus] |
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No pathways have been reviewed or authored by GFRalpha receptors GFRalpha1 and possibly also GFRalpha2 and... (375053)
