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Details on Person In myoblasts, CDO forms cis complexes with the cell–cell adh...

Class:IdSummation:375027
_displayNameIn myoblasts, CDO forms cis complexes with the cell–cell adh...
_timestamp2016-09-30 21:28:51
created[InstanceEdit:375044] Garapati, P V, 2008-08-11 10:27:37
literatureReference[LiteratureReference:375051] Netrins and neogenin promote myotube formation
modified[InstanceEdit:448801] Garapati, P V, 2009-11-26
[InstanceEdit:453163] Garapati, P V, 2010-01-19
[InstanceEdit:525774] Garapati, P V, 2010-02-21
textIn myoblasts, CDO forms cis complexes with the cell–cell adhesion molecule N-cadherin, which is itself involved in regulation of myogenesis. These cadherin complexes contain beta- and alpha-catenins which are important for N-cadherin's effect in myoblast. When CDO binds with ligated cadherins, its intracellular region undergoes a change in conformation and/or posttranslational modi?cation that permits its stable association with Bnip-2 and JLP and, consequently, activation of p38.
(summation)[Reaction:375140] CDO binds promyogenic cadherins [Homo sapiens]
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