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Details on Person Mechanism of GTP hydrolysis by G-protein alpha subunits

Class:IdLiteratureReference:374843
_displayNameMechanism of GTP hydrolysis by G-protein alpha subunits
_timestamp2008-08-01 09:30:39
author[Person:374809] Kleuss, C
[Person:374833] Raw, AS
[Person:207457] Lee, E
[Person:374816] Sprang, SR
[Person:374844] Gilman, AG
created[InstanceEdit:374823] Jassal, B, 2008-08-01 09:28:11
journalProc Natl Acad Sci U S A
modified[InstanceEdit:374846] Jassal, B, 2008-08-01 09:30:06
pages9828-31
pubMedIdentifier7937899
titleMechanism of GTP hydrolysis by G-protein alpha subunits
volume91
year1994
(literatureReference)[Summation:400669] When a ligand activates a G protein-coupled receptor, it ind...
[Reaction:167415] G-protein alpha subunit is inactivated [Homo sapiens]
[Reaction:170666] Adenylate cyclase increases the GTPase activity of G alpha-olf [Homo sapiens]
[Reaction:170674] Dissociation of the Gi alpha:G olf complex [Homo sapiens]
[Reaction:170677] The G alpha-olf:GDP:Adenylate cyclase complex dissociates [Homo sapiens]
[Reaction:170685] Adenylaye cyclase increases the GTPase activity of G alpha-olf [Homo sapiens]
[Reaction:170686] Adenylate cyclase increases the GTPase activity of Gi alpha [Homo sapiens]
[Reaction:392133] G alpha (z) auto-inactivates by hydrolysing GTP to GDP [Homo sapiens]
[Reaction:392212] G alpha (i) auto-inactivates by hydrolysing GTP to GDP [Homo sapiens]
[Reaction:418574] G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP [Homo sapiens]
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No pathways have been reviewed or authored by Mechanism of GTP hydrolysis by G-protein alpha subunits (374843)