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Details on Person Nephrin interacts with Podocin

Class:Id	Reaction:373734
_displayName	Nephrin interacts with Podocin
_doRelease	TRUE
_timestamp	2012-03-23 14:59:05
authored	[InstanceEdit:214881] de Bono, B, Garapati, P V, 2008-02-26 12:30:30
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:373728] Garapati, P V, 2008-07-16 14:41:14
edited	[InstanceEdit:532602] Garapati, P V, 2010-03-01
entityOnOtherCell	[EntityWithAccessionedSequence:197692] NPHS1-1 [plasma membrane] [Homo sapiens]
input	[Complex:374555] p-Y1158,Y1176,Y1193,Y1217-NPHS1:KIRREL:FYN [plasma membrane] [Homo sapiens] [Polymer:451771] Podocin oligomer [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:373482] Interaction with podocin facilitates nephrin signaling [LiteratureReference:373554] Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin [LiteratureReference:936057] Molecular basis of the functional podocin-nephrin complex: mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains
modified	[InstanceEdit:388580] Garapati, P V, 2008-12-16 10:09:03 [InstanceEdit:451406] Garapati, P V, 2010-01-05 [InstanceEdit:451759] Garapati, P V, 2010-01-11 [InstanceEdit:451770] Garapati, P V, 2010-01-12 [InstanceEdit:532597] Garapati, P V, 2010-03-01 [InstanceEdit:765030] Garapati, P V, 2010-05-20 [InstanceEdit:847688] Garapati, P V, 2010-05-30 [InstanceEdit:933340] Garapati, P V, 2010-08-10 [InstanceEdit:936071] Garapati, P V, 2010-08-22 [InstanceEdit:2167920] Garapati, P V, 2012-03-23 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Nephrin interacts with Podocin
output	[Complex:373691] Podocin:p-Nephrin:Fyn:NEPH1 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:373747] Phosphorylation of nephrin by FYN [Homo sapiens] [Reaction:8981534] Nephrin dimer:KIRREL binds FYN [Homo sapiens]
releaseDate	2010-09-21
reviewed	[InstanceEdit:765028] Huber, TB, Grahammer, Florian, 2010-05-20
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1104552] R-HSA-373734.2
summation	[Summation:373591] NPHS2 encodes podocin, a protein exclusively expressed in po...
(hasEvent)	[Pathway:373753] Nephrin family interactions [Homo sapiens]
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No pathways have been reviewed or authored by Nephrin interacts with Podocin (373734)