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Details on Person Cytosolic lactate dehydrogenase catalyzes the reversible rea...
| Class:Id | Summation:372907 |
|---|---|
| _displayName | Cytosolic lactate dehydrogenase catalyzes the reversible rea... |
| _timestamp | 2008-07-09 15:02:26 |
| created | [InstanceEdit:372894] D'Eustachio, P, 2008-07-09 15:02:13 |
| modified | [InstanceEdit:372912] D'Eustachio, P, 2008-07-09 15:02:29 |
| text | Cytosolic lactate dehydrogenase catalyzes the reversible reaction of lactate and NAD+ to form pyruvate and NADH + H+. There are two isoforms of lactate dehydrogenase encoded by two different genes whose expression levels vary from tissue to tissue and as a function of developmental stage. The active form of the enzyme is a tetramer, whose composition in a tissue appears to be determined by the relative abundances of the two monomer isoforms. All five possible lactate dehydrogenase isoforms have been described; no functional differences among them have been found (Lindsay 1963; Hirota et al. 1990). |
| (summation) | [Reaction:372903] lactate + NAD+ <=> pyruvate + NADH + H+ [Gallus gallus] |
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No pathways have been reviewed or authored by Cytosolic lactate dehydrogenase catalyzes the reversible rea... (372907)
