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Details on Person PCK2 phosphorylates OA to yield PEP

Class:IdReaction:372819
_displayNamePCK2 phosphorylates OA to yield PEP
_doReleaseTRUE
_timestamp2025-01-02 09:29:19
authored[InstanceEdit:377490] D'Eustachio, P, 2008-09-12 21:47:19
catalystActivity[CatalystActivity:372821] phosphoenolpyruvate carboxykinase (GTP) activity of PCK2 [mitochondrial matrix]
catalystActivityReference[CatalystActivityReference:9815674] phosphoenolpyruvate carboxykinase (GTP) activity of PCK2 [mitochondrial matrix] Human mitochondrial phosphoenolpyruvate carboxykinase 2 gene. Structure, chromosomal localization and tissue-specific expression
compartment[Compartment:5460] mitochondrial matrix
created[InstanceEdit:372814] D'Eustachio, P, 2008-07-03 22:06:56
crossReference[DatabaseIdentifier:9933539] RHEA:10389
edited[InstanceEdit:377490] D'Eustachio, P, 2008-09-12 21:47:19
input[SimpleEntity:113587] OA [mitochondrial matrix]
[SimpleEntity:113573] GTP [mitochondrial matrix]
literatureReference[LiteratureReference:372816] Human mitochondrial phosphoenolpyruvate carboxykinase 2 gene. Structure, chromosomal localization and tissue-specific expression
[LiteratureReference:372808] Molecular cloning, sequencing and expression of the cDNA of the mitochondrial form of phosphoenolpyruvate carboxykinase from human liver
modified[InstanceEdit:376424] D'Eustachio, P, 2008-09-06 21:22:36
[InstanceEdit:376871] D'Eustachio, P, 2008-09-10 19:02:07
[InstanceEdit:377489] D'Eustachio, P, 2008-09-12 21:56:09
[InstanceEdit:9815667] D'Eustachio, Peter, 2022-08-25
[InstanceEdit:9815858] D'Eustachio, Peter, 2022-08-29
[InstanceEdit:9815861] D'Eustachio, Peter, 2022-08-29
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9933541] Stephan, Ralf, 2025-01-02
namePCK2 phosphorylates OA to yield PEP
GTP + oxaloacetate => CO2 + GDP + phosphoenolpyruvate
output[SimpleEntity:372364] PEP [mitochondrial matrix]
[SimpleEntity:29376] CO2 [mitochondrial matrix]
[SimpleEntity:113525] GDP [mitochondrial matrix]
precedingEvent
releaseDate2008-09-30
reviewed[InstanceEdit:376870] Harris, RA, 2008-09-10 18:47:12
[InstanceEdit:9815859] Hill, David P, 2022-08-29
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:9815860] D'Eustachio, Peter, 2022-08-29
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:377918] R-HSA-372819.4
summation[Summation:372809] PCK2 (phosphoenolcarboxykinase), located in the mitochondria...
(hasEvent)[Pathway:70263] Gluconeogenesis [Homo sapiens]
(precedingEvent)[Reaction:372449] SLC25A1 may exchange mitochondrial PEP for cytosolic anion [Homo sapiens]
(updatedInstance)[_UpdateTracker:9846851] Update Tracker - [Reaction:372819] PCK2 phosphorylates OA to yield PEP - v83:[modifyText]
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No pathways have been reviewed or authored by PCK2 phosphorylates OA to yield PEP (372819)
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