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Details on Person aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate

Class:Id	Reaction:372719
_displayName	aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate
_doRelease	TRUE
_timestamp	2011-11-23 11:09:51
authored	[InstanceEdit:376875] D'Eustachio, P, 2008-09-10 19:15:11
catalystActivity	[CatalystActivity:372599] L-aspartate:2-oxoglutarate transaminase activity of GOT1 dimer [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:372727] D'Eustachio, P, 2008-06-27 20:07:42
edited	[InstanceEdit:376875] D'Eustachio, P, 2008-09-10 19:15:11
input	[SimpleEntity:29448] L-Asp [cytosol] [SimpleEntity:29406] 2OG [cytosol]
literatureReference	[LiteratureReference:372721] Primary structure of cytoplasmic aspartate aminotransferase from chicken heart and its homology with pig heart isoenzymes
modified	[InstanceEdit:372925] D'Eustachio, P, 2008-07-09 18:44:21 [InstanceEdit:376849] D'Eustachio, P, 2008-09-09 16:42:31 [InstanceEdit:418476] D'Eustachio, P, 2009-04-22 20:40:00 [InstanceEdit:418568] D'Eustachio, P, 2009-04-23 19:25:43 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate Transamination of aspartate and alpha-ketoglutarate (2-oxoglutarate) to form oxaloacetate + glutamate
output	[SimpleEntity:76213] OA [cytosol] [SimpleEntity:29404] L-Glu [cytosol]
precedingEvent	[Reaction:372726] aspartate [mitochondrial matrix] + glutamate [cytosol] <=> aspartate [cytosol] + glutamate [mitochondrial matrix] [Gallus gallus] [Reaction:372564] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) [Gallus gallus] [Reaction:372742] 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] [Gallus gallus]
releaseDate	2009-06-01
reverseReaction	[Reaction:372717] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) [Gallus gallus] [Reaction:372719] aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate [Gallus gallus]
reviewed	[InstanceEdit:376870] Harris, RA, 2008-09-10 18:47:12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:49591] Gallus gallus
stableIdentifier	[StableIdentifier:2016331] R-GGA-372719.2
summation	[Summation:372720] Cytosolic GOT1 catalyzes the reversible transamination of as...
(hasEvent)	[Pathway:352875] Gluconeogenesis [Gallus gallus] [Pathway:372568] Amino acid metabolism [Gallus gallus]
(precedingEvent)	[Reaction:372741] oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [cytosol] [Gallus gallus]
(reverseReaction)	[Reaction:372717] oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) [Gallus gallus]
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No pathways have been reviewed or authored by aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate (372719)