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Details on Person Phosphorylation of BCAR1 by SRC-PTK2 complex

Class:IdReaction:372693
_displayNamePhosphorylation of BCAR1 by SRC-PTK2 complex
_doReleaseTRUE
_timestamp2019-01-14 20:18:39
authored[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
catalystActivity[CatalystActivity:372641] protein tyrosine kinase activity of BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:372695] Garapati, P V, 2008-06-27 10:21:48
edited[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
input[Complex:372688] BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:372665] p130Cas: a versatile scaffold in signaling networks
[LiteratureReference:215835] Bidirectional integrin alphaIIbbeta3 signalling regulating platelet adhesion under flow: contribution of protein kinase C
[LiteratureReference:372692] Focal adhesion kinase: the first ten years
[LiteratureReference:5693305] Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase
modified[InstanceEdit:373929] Garapati, P V, 2008-07-18 08:42:42
[InstanceEdit:373944] Garapati, P V, 2008-07-22 08:38:50
[InstanceEdit:377698] Garapati, P V, 2008-09-16 06:33:14
[InstanceEdit:383277] Garapati, P V, 2008-11-24 15:56:52
[InstanceEdit:939908] Jupe, S, 2010-09-02
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:5693302] Garapati, Phani Vijay, 2015-05-14
[InstanceEdit:9634743] Rothfels, Karen, 2019-01-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePhosphorylation of BCAR1 by SRC-PTK2 complex
output[Complex:372646] p-BCAR1:Talin:RIAM:ECM ligands:alphaIIb beta3:p-Y419 SRC:p-6Y-PTK2 [plasma membrane] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2008-12-17
reviewed[InstanceEdit:377695] Shattil, SJ, 2008-09-16 06:21:39
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:387639] R-HSA-372693.3
summation[Summation:372682] SH3-mediated binding of BCAR1/p130Cas to PTK2 is linked to e...
(hasEvent)[Pathway:372708] p130Cas linkage to MAPK signaling for integrins [Homo sapiens]
(precedingEvent)[Reaction:372697] Crk binding to p130cas [Homo sapiens]
(updatedInstance)[_UpdateTracker:9778603] Update Tracker - [Reaction:372693] Phosphorylation of BCAR1 by SRC-PTK2 complex - v68:[modifyText]
[_UpdateTracker:9782456] Update Tracker - [Reaction:372693] Phosphorylation of BCAR1 by SRC-PTK2 complex - v59:[modifyText]
[_UpdateTracker:9784573] Update Tracker - [Reaction:372693] Phosphorylation of BCAR1 by SRC-PTK2 complex - v53:[addLiteratureReference]
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