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Details on Person TP53 R175H does not bind BAX promoter

Class:Id	FailedReaction:3701023
_displayName	TP53 R175H does not bind BAX promoter
_doRelease	FALSE
_timestamp	2018-11-28 21:10:29
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3701012] Orlic-Milacic, M, 2013-06-11
disease	[Disease:1500689] cancer
entityFunctionalStatus	[EntityFunctionalStatus:3701017] loss_of_function of TP53 R175H Tetramer [nucleoplasm]
input	[Complex:3701024] TP53 R175H Tetramer [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:3700977] BAX gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:3701015] Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9630111] Orlic-Milacic, Marija, 2018-11-28
name	TP53 R175H does not bind BAX promoter
normalReaction	[Reaction:3700981] TP53 family members bind the BAX promoter [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8911302] R-HSA-3701023.1
(hasEvent)	[Pathway:3701007] Transcriptional Regulation by TP53 R175H [Homo sapiens]
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No pathways have been reviewed or authored by TP53 R175H does not bind BAX promoter (3701023)