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Details on Person PRDX5 reduces peroxynitrite to nitrite using TXN

Class:Id	Reaction:3697882
_displayName	PRDX5 reduces peroxynitrite to nitrite using TXN
_doRelease	TRUE
_timestamp	2014-11-20 02:36:37
authored	[InstanceEdit:3697837] May, B, 2013-06-09
catalystActivity	[CatalystActivity:3697876] thioredoxin peroxidase activity of PRDX5 [cytosol]
catalystActivityReference	[CatalystActivityReference:9643539] thioredoxin peroxidase activity of PRDX5 [cytosol] Human peroxiredoxin 5 is a peroxynitrite reductase
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:3697867] May, B, 2013-06-09
edited	[InstanceEdit:3697837] May, B, 2013-06-09
input	[SimpleEntity:1222481] Peroxynitrite [cytosol] [EntityWithAccessionedSequence:66000] TXN [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:3697879] Human peroxiredoxin 5 is a peroxynitrite reductase
modified	[InstanceEdit:3779419] May, B, 2013-06-27 [InstanceEdit:3780990] May, B, 2013-06-27 [InstanceEdit:4415003] May, B, 2013-08-23 [InstanceEdit:4420243] May, B, 2013-08-31 [InstanceEdit:4837349] May, B, 2013-11-01 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PRDX5 reduces peroxynitrite to nitrite using TXN
output	[SimpleEntity:1222379] Nitrite [cytosol] [SimpleEntity:29356] H2O [cytosol] [EntityWithAccessionedSequence:73668] 2xHC-TXN [cytosol] [Homo sapiens]
precedingEvent	[Reaction:1222407] Superoxide and nitric oxide react to peroxynitrite [Homo sapiens] [Reaction:1222376] NOX2 generates superoxide from oxygen [Homo sapiens] [Reaction:418436] Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) [Homo sapiens] [Reaction:73646] Regeneration of active (reduced) Thioredoxin [Homo sapiens]
releaseDate	2013-12-04
reviewed	[InstanceEdit:4837339] Kavdia, Mahendra, 2013-11-01
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644402] R-HSA-3697882.3
summation	[Summation:3779366] Peroxiredoxin 5 (PRDX5) very efficiently reduces peroxynitri...
(hasEvent)	[Pathway:3299685] Detoxification of Reactive Oxygen Species [Homo sapiens]
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No pathways have been reviewed or authored by PRDX5 reduces peroxynitrite to nitrite using TXN (3697882)