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Details on Person EP300 acetylates histone H2A, H2B, H3, H4

Class:Id	Reaction:3662335
_displayName	EP300 acetylates histone H2A, H2B, H3, H4
_doRelease	TRUE
_timestamp	2015-03-04 03:50:02
authored	[InstanceEdit:3214866] Jupe, S, 2013-03-12
catalystActivity	[CatalystActivity:3662301] histone acetyltransferase activity of EP300 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3662332] Jupe, S, 2013-06-07
edited	[InstanceEdit:5146786] Jupe, S, 2013-11-18
input	[CandidateSet:4568580] Histone H2A, H2B, H3, H4 [nucleoplasm] [Homo sapiens] [SimpleEntity:113560] Ac-CoA [nucleoplasm]
isChimeric	FALSE
literatureReference	[LiteratureReference:3301253] Overlapping but distinct patterns of histone acetylation by the human coactivators p300 and PCAF within nucleosomal substrates
modified	[InstanceEdit:3662339] Jupe, S, 2013-06-07 [InstanceEdit:3697937] Jupe, S, 2013-06-10 [InstanceEdit:4568588] Jupe, S, 2013-09-16 [InstanceEdit:4568767] Jupe, S, 2013-09-18 [InstanceEdit:4960919] Jupe, S, 2013-11-04 [InstanceEdit:5144556] Jupe, S, 2013-11-18 [InstanceEdit:5146784] Jupe, S, 2013-11-18 [InstanceEdit:5146786] Jupe, S, 2013-11-18 [InstanceEdit:5149551] Matthews, L, 2013-11-20 [InstanceEdit:5674563] Jupe, Steve, 2015-02-13 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	EP300 acetylates histone H2A, H2B, H3, H4
output	[CandidateSet:4568601] AcK-histone H2A, H2B, H3, H4 [nucleoplasm] [Homo sapiens] [SimpleEntity:2485002] CoA-SH [nucleoplasm]
releaseDate	2013-12-04
reviewed	[InstanceEdit:5144557] Karagiannis, Tom, 2013-11-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644858] R-HSA-3662335.2
summation	[Summation:3697917] EP300 and the related CREBBP are transcriptional regulators ...
(hasEvent)	[Pathway:3214847] HATs acetylate histones [Homo sapiens]
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No pathways have been reviewed or authored by EP300 acetylates histone H2A, H2B, H3, H4 (3662335)