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Details on Person Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin
| Class:Id | LiteratureReference:3640789 |
| _displayName | Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin |
| _timestamp | 2018-07-12 19:37:33 |
| author | [Person:3640671] Ikeda, Satoshi [Person:3640674] Kishida, Shosei [Person:3238067] Yamamoto, Hideki [Person:3640717] Murai, Hiroshi [Person:3640677] Koyama, Shinya [Person:4640987] Kikuchi, Akira |
| created | [InstanceEdit:3640788] Rothfels, K, 2013-05-29 |
| journal | EMBO J. |
| modified | [InstanceEdit:9613273] D'Eustachio, Peter, 2018-07-12 |
| pages | 1371-84 |
| pubMedIdentifier | 9482734 |
| title | Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin |
| volume | 17 |
| year | 1998 |
| (literatureReference) | [Reaction:209096] Murine Axin1 is dephosphorylated by PP2A leading to reduced binding affinity with beta-catenin [Mus musculus] [BlackBoxEvent:3601585] PP2A dephosphorylates AXIN, APC and CTNNB1 in the destruction complex [Homo sapiens] [Reaction:5229343] AXIN is phosphorylated in the destruction complex [Homo sapiens] |
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