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Details on Person UniProt:Q86XT9 TMEM219
| Class:Id | ReferenceGeneProduct:357617 |
|---|---|
| _chainChangeLog | signal peptide:1-38 added on Sat February 7 2015;chain:39-240 added on Sat February 7 2015 |
| _displayName | UniProt:Q86XT9 TMEM219 |
| _timestamp | 2024-11-03 20:17:07 |
| chain | signal peptide:1-38 chain:39-240 |
| checksum | 8985EB036BB37EE8 |
| comment | FUNCTION Cell death receptor specific for IGFBP3, may mediate caspase-8-dependent apoptosis upon ligand binding.SUBUNIT Interacts with IGFBP3. Interacts with CASP8.INTERACTION Widely expressed in normal tissues but suppressed in prostate and breast tumor. |
| created | [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12 |
| description | recommendedName: Insulin-like growth factor-binding protein 3 receptor shortName: IGFBP-3R alternativeName: Transmembrane protein 219 |
| geneName | TMEM219 |
| identifier | Q86XT9 |
| isSequenceChanged | FALSE |
| keyword | Apoptosis Cell membrane Glycoprotein Membrane Proteomics identification Receptor Reference proteome Signal Transmembrane Transmembrane helix |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | TMEM219 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8997486] ENSEMBL:ENSG00000149932 TMEM219 [Homo sapiens] |
| secondaryIdentifier | TM219_HUMAN D5FK14 Q8WVV8 |
| sequenceLength | 240 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:6800018] TMEM219 [plasma membrane] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q86XT9 TMEM219 (357617)
