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Details on Person UniProt:Q8IZS6 DYNLT2
| Class:Id | ReferenceGeneProduct:356913 |
|---|---|
| _chainChangeLog | chain:1-198 added on Fri February 6 2015 |
| _displayName | UniProt:Q8IZS6 DYNLT2 |
| _timestamp | 2026-02-20 21:58:33 |
| chain | chain:1-198 |
| checksum | FC20E7C32510111D |
| comment | FUNCTION Component of dynein, a family of motor proteins essential for movement along microtubules (PubMed:11278908, PubMed:12584439). Required for structural and functional integrity of cilia (By similarity). Candidate for involvement in male sterility (By similarity).SUBUNIT Part of the ciliary outer dynein arms (ODAs), at least consisting of dynein axonemal heavy chains, light chains and intermediate chains (By similarity). The ODAs interacts with DNAAF9; this interaction inactivates the dyneins (By similarity). Interacts with CCDC159 (By similarity). Interacts with CSNK2B (By similarity).INTERACTION Found on the surface of sperm tail. Stored in cytoplasmic granules during spermatogenesis.TISSUE SPECIFICITY Expressed predominantly in testis. Also expressed in brain, lung and trachea.SIMILARITY Belongs to the dynein light chain Tctex-type family. |
| created | [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12 |
| description | recommendedName: fullName evidence="6"Dynein light chain Tctex-type protein 2 alternativeName: T-complex testis-specific protein 3 alternativeName: T-complex-associated testis-expressed protein 3 shortName: Tcte-3 alternativeName: Tctex1 domain-containing protein 3 |
| geneName | DYNLT2 TCTE3 TCTEX1D3 |
| identifier | Q8IZS6 |
| isSequenceChanged | FALSE |
| keyword | Cytoplasm Cytoskeleton Dynein Membrane Microtubule Motor protein Proteomics identification Reference proteome Transport |
| modified | [InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39 [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:8987656] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9657908] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9715482] Weiser, JD [InstanceEdit:9750299] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 |
| name | DYNLT2 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8998634] ENSEMBL:ENSG00000184786 DYNLT2 [Homo sapiens] |
| secondaryIdentifier | DYLT2_HUMAN |
| sequenceLength | 198 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:5624885] DYNLT2 [cilium] [Homo sapiens] [EntityWithAccessionedSequence:5625398] DYNLT2 [ciliary tip] [Homo sapiens] [EntityWithAccessionedSequence:9969293] DYNLT2 [cytosol] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:Q8IZS6 DYNLT2 (356913)
