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Details on Person UniProt:Q3ZBD0 PSMD7
| Class:Id | ReferenceGeneProduct:356312 |
|---|---|
| _chainChangeLog | chain:1-322 added on Sat February 7 2015 |
| _displayName | UniProt:Q3ZBD0 PSMD7 |
| _timestamp | 2023-11-03 17:33:16 |
| chain | chain:1-322 |
| checksum | FB9B2F8A601FB860 |
| comment | FUNCTION Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.SUBUNIT Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD7, a base containing 6 ATPases and few additional components. Within the complex, PSMD7 interacts with subunit PSMD4 through their respective MPN domain. Interacts with TRIM5.MISCELLANEOUS Does not bind a metal ion.SIMILARITY Belongs to the peptidase M67A family. |
| created | [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12 |
| description | recommendedName: 26S proteasome non-ATPase regulatory subunit 7 alternativeName: 26S proteasome regulatory subunit RPN8 |
| geneName | PSMD7 |
| identifier | Q3ZBD0 |
| isSequenceChanged | FALSE |
| keyword | Acetylation Isopeptide bond Proteasome Reference proteome Ubl conjugation |
| modified | [InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39 [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:3445779] Weiser, JD [InstanceEdit:4341137] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | PSMD7 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | PSMD7_BOVIN |
| sequenceLength | 322 |
| species | [Species:48898] Bos taurus |
| (referenceEntity) | [EntityWithAccessionedSequence:9918591] bPSMD7 [cytosol] [Bos taurus] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q3ZBD0 PSMD7 (356312)
