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Details on Person UniProt:Q96H55-3 MYO19
| Class:Id | ReferenceIsoform:355960 |
|---|---|
| _chainChangeLog | chain:1-970 added on Sat February 7 2015 |
| _displayName | UniProt:Q96H55-3 MYO19 |
| _timestamp | 2024-11-03 19:42:05 |
| chain | chain:1-970 |
| checksum | 3AB15AD901BE7407 |
| comment | FUNCTION Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane (PubMed:19932026, PubMed:23568824, PubMed:25447992). Motor protein that moves towards the plus-end of actin filaments (By similarity). Required for mitochondrial inheritance during mitosis (PubMed:25447992). May be involved in mitochondrial transport or positioning (PubMed:23568824).SUBUNIT Myosin is a hexamer of 2 heavy chains and 4 light chains: interacts with myosin light chains MYL9 and MYL12B.SUBCELLULAR LOCATION Widely expressed in multiple tissues and cell lines.DOMAIN The MyMOMA (MYO19-specific mitochondrial outer membrane-association) region mediates association with the mitochondrion outer membrane via electrostatic interaction.SIMILARITY Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. |
| created | [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12 |
| description | recommendedName: fullName evidence="12"Unconventional myosin-XIX alternativeName: fullName evidence="16"Myosin head domain-containing protein 1 |
| geneName | MYO19 MYOHD1 |
| identifier | Q96H55 |
| isoformParent | |
| isSequenceChanged | FALSE |
| keyword | Actin-binding Alternative splicing ATP-binding Cytoplasm Cytoskeleton Membrane Mitochondrion Mitochondrion outer membrane Motor protein Myosin Nucleotide-binding Phosphoprotein Proteomics identification Reference proteome Repeat |
| modified | [InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39 [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:8934940] Weiser, JD [InstanceEdit:8987656] Weiser, JD [InstanceEdit:9015733] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9715482] Weiser, JD [InstanceEdit:9730071] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | MYO19 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8997287] ENSEMBL:ENSG00000278259 MYO19 [Homo sapiens] |
| secondaryIdentifier | MYO19_HUMAN Q59GS4 Q9H5X2 |
| sequenceLength | 970 |
| species | [Species:48887] Homo sapiens |
| variantIdentifier | Q96H55-3 |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q96H55-3 MYO19 (355960)
