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Details on Person UniProt:Q96H55 MYO19
Class:Id
ReferenceGeneProduct:355958
_chainChangeLog
chain:1-970 added on Sat February 7 2015
_displayName
UniProt:Q96H55 MYO19
_timestamp
2024-11-03 19:42:04
chain
chain:1-970
checksum
3AB15AD901BE7407
comment
FUNCTION Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane (PubMed:19932026, PubMed:23568824, PubMed:25447992). Motor protein that moves towards the plus-end of actin filaments (By similarity). Required for mitochondrial inheritance during mitosis (PubMed:25447992). May be involved in mitochondrial transport or positioning (PubMed:23568824).SUBUNIT Myosin is a hexamer of 2 heavy chains and 4 light chains: interacts with myosin light chains MYL9 and MYL12B.SUBCELLULAR LOCATION Widely expressed in multiple tissues and cell lines.DOMAIN The MyMOMA (MYO19-specific mitochondrial outer membrane-association) region mediates association with the mitochondrion outer membrane via electrostatic interaction.SIMILARITY Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
