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Details on Person AlphaIIbbeta3 mediated nucleotide exchange of RAS (SHC)

Class:Id	Reaction:354152
_displayName	AlphaIIbbeta3 mediated nucleotide exchange of RAS (SHC)
_doRelease	FALSE
_timestamp	2016-12-01 00:31:34
authored	[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
catalystActivity	[CatalystActivity:354134] guanyl-nucleotide exchange factor activity of GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane]
compartment	[Compartment:947587] cytoplasmic side of plasma membrane
created	[InstanceEdit:354078] Garapati, P V, 2008-06-16 17:02:05
inferredFrom	[Reaction:112378] SOS mediated nucleotide exchange of RAS (SHC) [Rattus norvegicus]
input	[Complex:109796] p21 RAS:GDP [plasma membrane] [Homo sapiens] [SimpleEntity:29438] GTP [cytosol]
literatureReference	[LiteratureReference:187761] The structural basis of the activation of Ras by Sos
modified	[InstanceEdit:373927] Garapati, P V, 2008-07-18 08:38:54 [InstanceEdit:373941] Garapati, P V, 2008-07-22 08:37:08 [InstanceEdit:377648] Garapati, P V, 2008-09-15 19:03:41 [InstanceEdit:5255454] D'Eustachio, Peter, 2014-02-06 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8949915] D'Eustachio, Peter, 2016-12-01
name	AlphaIIbbeta3 mediated nucleotide exchange of RAS (SHC)
output	[Complex:109783] p21 RAS:GTP [plasma membrane] [Homo sapiens] [SimpleEntity:29420] GDP [cytosol]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8923872] R-HSA-354152.1
summation	[Summation:354058] Sos-1 bound to Grb2:FAK:Integrin complex promotes the exchan...
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No pathways have been reviewed or authored by AlphaIIbbeta3 mediated nucleotide exchange of RAS (SHC) (354152)