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Details on Person Phosphorylation of pPTK2 by SRC

Class:IdReaction:354124
_displayNamePhosphorylation of pPTK2 by SRC
_doReleaseTRUE
_timestamp2019-01-14 20:18:42
authored[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
catalystActivity[CatalystActivity:354090] protein tyrosine kinase activity of Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:354078] Garapati, P V, 2008-06-16 17:02:05
edited[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
input[Complex:354135] Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:354120] Biochemical signals and biological responses elicited by the focal adhesion kinase
[LiteratureReference:354182] Integrin-regulated FAK-Src signaling in normal and cancer cells
modified[InstanceEdit:354203] Garapati, P V, 2008-06-16 17:32:15
[InstanceEdit:372628] Garapati, P V, 2008-06-27 10:02:16
[InstanceEdit:373160] Garapati, P V, 2008-07-14 14:08:59
[InstanceEdit:373930] Garapati, P V, 2008-07-18 08:43:11
[InstanceEdit:373944] Garapati, P V, 2008-07-22 08:38:50
[InstanceEdit:377653] Garapati, P V, 2008-09-15 19:04:36
[InstanceEdit:377698] Garapati, P V, 2008-09-16 06:33:14
[InstanceEdit:383277] Garapati, P V, 2008-11-24 15:56:52
[InstanceEdit:939908] Jupe, S, 2010-09-02
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9634744] Rothfels, Karen, 2019-01-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePhosphorylation of pPTK2 by SRC
output[Complex:354080] Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2008-12-17
reviewed[InstanceEdit:377695] Shattil, SJ, 2008-09-16 06:21:39
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:387632] R-HSA-354124.3
summation[Summation:372627] The recruitment of FADK1 to active SRC leads to the efficien...
(hasEvent)[Pathway:354192] Integrin signaling [Homo sapiens]
(precedingEvent)[Reaction:354087] Recruitment of GRB2 to p-PTK2 [Homo sapiens]
[Reaction:372705] Recruitment of BCAR1 to PTK2 complex [Homo sapiens]
(updatedInstance)[_UpdateTracker:9790269] Update Tracker - [Reaction:354124] Phosphorylation of pPTK2 by SRC - v34:[modifyText]
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