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Details on Person Integrin alphaIIb beta3 activation

Class:Id	Reaction:354077
_displayName	Integrin alphaIIb beta3 activation
_doRelease	TRUE
_timestamp	2011-02-13 15:49:55
authored	[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:354078] Garapati, P V, 2008-06-16 17:02:05
edited	[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
input	[Complex:354176] Talin:RIAM complex [plasma membrane] [Homo sapiens] [Complex:377608] Integrin alphaIIb beta3:p-Y530-SRC:CSK [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:354084] Talin at a glance [LiteratureReference:354175] Integrin activation [LiteratureReference:354127] Integrin signaling [LiteratureReference:377584] Structural basis of integrin activation by talin [LiteratureReference:429426] Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton
modified	[InstanceEdit:373928] Garapati, P V, 2008-07-18 08:41:13 [InstanceEdit:373942] Garapati, P V, 2008-07-22 08:37:55 [InstanceEdit:377655] Garapati, P V, 2008-09-15 19:05:03 [InstanceEdit:377701] Garapati, P V, 2008-09-16 06:35:26 [InstanceEdit:383279] Garapati, P V, 2008-11-24 15:57:36 [InstanceEdit:939908] Jupe, S, 2010-09-02 [InstanceEdit:1215936] Garapati, P V, 2011-02-13 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Integrin alphaIIb beta3 activation
output	[Complex:354130] Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:354097] Activation of Talin [Homo sapiens] [Reaction:354060] Translocation of RIAM to plasma membrane [Homo sapiens]
releaseDate	2008-12-17
reviewed	[InstanceEdit:377695] Shattil, SJ, 2008-09-16 06:21:39
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:387751] R-HSA-354077.2
summation	[Summation:354102] The interaction between talin and integrin alphaIIb beta3 br...
(hasEvent)	[Pathway:354192] Integrin signaling [Homo sapiens]
(precedingEvent)	[Reaction:354149] Interaction of integrin alphaIIb beta3 with Fibrinogen [Homo sapiens] [Reaction:432096] Activated integrin alphaIIb beta3 binds SHC1 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9789915] Update Tracker - [Reaction:354077] Integrin alphaIIb beta3 activation - v36:[addLiteratureReference, modifyText] [_UpdateTracker:9790256] Update Tracker - [Reaction:354077] Integrin alphaIIb beta3 activation - v34:[modifyText]
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No pathways have been reviewed or authored by Integrin alphaIIb beta3 activation (354077)