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Details on Person p-Y397-PTK2 [cytosol]
Class:Id EntityWithAccessionedSequence:354068
_displayName p-Y397-PTK2 [cytosol]
_timestamp 2015-01-05 16:29:33
compartment [Compartment:70101] cytosol
created [InstanceEdit:354078] Garapati, P V, 2008-06-16 17:02:05
endCoordinate 1052
hasModifiedResidue [ModifiedResidue:354088] O4'-phospho-L-tyrosine at 397
modified [InstanceEdit:387214] Garapati, P V, 2008-12-01 13:13:07 [InstanceEdit:939908] Jupe, S, 2010-09-02 [InstanceEdit:3008640] D'Eustachio, P, 2013-02-01 [InstanceEdit:3132750] Wu, G, 2013-02-13 [InstanceEdit:3322333] Wu, G, 2013-05-03 [InstanceEdit:3322334] Wu, G, 2013-05-03 [InstanceEdit:5218752] Garapati, P V, 2013-12-19 [InstanceEdit:5660684] Jassal, Bijay, 2015-01-05
name p-Y397-PTK2 p-Y397-FAK1 auto phosphorylated FAK 1
referenceEntity [ReferenceGeneProduct:54648] UniProt:Q05397 PTK2 [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:387840] R-HSA-354068.1
startCoordinate 2
(hasComponent) [Complex:354135] Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] [Homo sapiens] [Complex:391841] pFAK (391) bound to NCAM1:pFyn [plasma membrane] [Homo sapiens] [Complex:418822] NTN1:DCC oligomer:p-Y397-PTK2 [plasma membrane] [Homo sapiens] [Complex:418839] NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2 [plasma membrane] [Homo sapiens] [Complex:3928549] EFNBs:p-EPHBs:p-Y397-PTK2 [plasma membrane] [Homo sapiens] [Complex:5218639] VEGFA:p-6Y-VEGFR2:p-SHB:p-Y397-PTK2 [plasma membrane] [Homo sapiens] [Complex:8874094] HGF:p-4Y-MET dimer:p-Y397-PTK2 [plasma membrane] [Homo sapiens] [Complex:9625464] EGF-like ligands:p-6Y EGFR dimer:p-Y397 PTK2 [plasma membrane] [Homo sapiens]
(output) [BlackBoxEvent:9861484] Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow [Homo sapiens]
(physicalEntity) [CatalystActivity:9865680] protein tyrosine kinase activity of p-Y397-PTK2 [cytosol]
(regulator) [PositiveRegulation:9861477] Positive regulation by 'p-Y397-PTK2 [cytosol]'
(requiredInputComponent) [Reaction:354147] Binding of Src to FADK1 [Homo sapiens]
(updatedInstance) [_UpdateTracker:9869616] Update Tracker - [EntityWithAccessionedSequence:354068] p-Y397-PTK2 [cytosol] - v34:[modifyName] [_UpdateTracker:9875722] Update Tracker - [EntityWithAccessionedSequence:354068] p-Y397-PTK2 [cytosol] - v44:[addName, modifyEndCoordinate, modifyStartCoordinate] [_UpdateTracker:9887215] Update Tracker - [EntityWithAccessionedSequence:354068] p-Y397-PTK2 [cytosol] - v45:[addName] [_UpdateTracker:9889220] Update Tracker - [EntityWithAccessionedSequence:354068] p-Y397-PTK2 [cytosol] - v48:[modifyName]
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Pathways
No pathways have been reviewed or authored by p-Y397-PTK2 [cytosol] (354068)