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Details on Person Translocation of PTK2 to Focal complexes

Class:Id	Reaction:354066
_displayName	Translocation of PTK2 to Focal complexes
_doRelease	TRUE
_timestamp	2019-01-14 20:19:02
authored	[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:354078] Garapati, P V, 2008-06-16 17:02:05
edited	[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
input	[EntityWithAccessionedSequence:201621] PTK2 [cytosol] [Homo sapiens] [Complex:377622] Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:354120] Biochemical signals and biological responses elicited by the focal adhesion kinase [LiteratureReference:354182] Integrin-regulated FAK-Src signaling in normal and cancer cells
modified	[InstanceEdit:372634] Garapati, P V, 2008-06-27 10:06:55 [InstanceEdit:373164] Garapati, P V, 2008-07-14 14:12:43 [InstanceEdit:373931] Garapati, P V, 2008-07-18 08:43:41 [InstanceEdit:373946] Garapati, P V, 2008-07-22 08:39:45 [InstanceEdit:377654] Garapati, P V, 2008-09-15 19:04:50 [InstanceEdit:377700] Garapati, P V, 2008-09-16 06:34:55 [InstanceEdit:383278] Garapati, P V, 2008-11-24 15:57:15 [InstanceEdit:387197] Garapati, P V, 2008-12-01 10:58:08 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:1215939] Garapati, P V, 2011-02-13 [InstanceEdit:9634753] Rothfels, Karen, 2019-01-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Translocation of PTK2 to Focal complexes
output	[Complex:354103] Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:377640] Autophosphorylation of SRC [Homo sapiens] [Reaction:377643] Dephosphorylation of inactive SRC by PTPB1 [Homo sapiens]
releaseDate	2008-12-17
reviewed	[InstanceEdit:377695] Shattil, SJ, 2008-09-16 06:21:39
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:387635] R-HSA-354066.3
summation	[Summation:372633] As integrins do not have an intrinsic catalytic activity, th...
(hasEvent)	[Pathway:354192] Integrin signaling [Homo sapiens]
(precedingEvent)	[Reaction:354073] Autophosphorylation of PTK2 at Y397 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9778377] Update Tracker - [Reaction:354066] Translocation of PTK2 to Focal complexes - v68:[modifyText] [_UpdateTracker:9790262] Update Tracker - [Reaction:354066] Translocation of PTK2 to Focal complexes - v34:[modifyText]
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